Injecting fat aspirate obtained during liposuction through a needle or thin cannula is a technique widely used on the aging face and sometimes in areas just above or below the eyelids (for instance, below the eyebrow or on the uppermost cheek). While such subcutaneous fat restoration can be very helpful in rebalancing shifting facial volume, injecting fat into the eyelids themselves to try to correct volume deficiency may yield disappointing results. Injecting fat into the orbit to correct deeper volume deficiency is dangerous and generally futile.

Anatomy of the facial skin
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The eyelid skin is quite different from other facial skin in that it is (1) much thinner and (2) essentially devoid of a normal subcutaneous fat layer. What is often referred to as "eyelid fat" is actually an extension of the orbital fat -- that is, the fat filling the orbit that cushions the eyeball in its socket. Diagrams
For facial skin other than on the eyelids, fat injected through a needle can be distributed into the deeper dermis, existing subcutaneous fat layer, and into or below the underlying muscle.
It is, however, very difficult to inject liposuctioned fat into its proper anatomic location in the orbit without risking injury to the eyeball and its surrounding blood vessels and muscles. Furthermore, injection techniques require many passes of the cannula to achieve a layering of pencil-thin cores of fat tightly surrounded by normal tissue. Because of the fragile and flexible nature of orbital tissue, injected fat instead tends to pool and not achieve the apposition needed for fast revascularization and survival.
If fat is injected into or just under the thin skin of the eyelid, it may disappear quickly or form visible lumps that are especially noticeable when a patient smiles or squints.
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Anatomy of eyelid skin
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Epidermis
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Dermis
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Subcutaneous fat
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Muscle below skin
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Surgical reversal, when indicated, is challenging because the injected fat infiltrates multiple delicate eyelid tissue layers and may be difficult to identify or remove without sacrificing some normal structure.
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While "microliposuction" may be employed (in essence, the reverse of the procedure used to inject the fat cells), unfortunately more than just the fat will be removed ("microtissuesuction" might be a better name). Sometimes, the only practical method of removal from the deeper eyelid is with surgery through a skin incision.
• Better for the face than for the eyelids
Thus, while fat injection of liposuction aspirate is a highly versatile technique that is useful in treating facial fat loss (including tear trough depressions on the uppermost cheek) and resupporting sagging skin, if the eyelids themselves appear hollowed due to a deficiency of orbital fat, fat transfer using structurally-intact pieces of adipose tissue (pearl fat grafting, strip fat grafting) seems preferable.
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Note: Dr. Meronk's practice is devoted entirely to cosmetic eyelid surgery. Since injection of liposuctioned fat is a technique better applied to the face, we do not offer this particular treatment. For facial fat balancing, you are best advised to seek advice from an experienced dermatologic or facial plastic surgeon.
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